Two more Big Horn County residents have been infected with COVID-19, with one of those patients testing positive at Powell Valley Healthcare.

The woman who was tested in Powell “is self-quarantined at home,” Park County Health Officer Dr. Aaron Billin said Saturday; no additional information was released about Saturday’s other confirmed case — a second Big Horn County woman who was tested at another location.

The Big Horn County Public Health Department and the Wyoming Department of Health have been working to determine who the two women had contact with, but “these cases are not thought to be related to other cases in our county,” Big Horn County officials said. There have now been seven confirmed cases of the new respiratory disease in the county.

The new cases underscore “the need to continue safe exposure reduction practices as have been emphasized throughout this emergency,” said a Saturday Facebook post from Big Horn County officials. “Community support and compliance is imperative at every level to protect our citizens. Safety is up to you.”

A Greybull restaurant announced Saturday that it was closing for at least four days while it awaited confirmation of a positive COVID-19 test on one of its employees.

“We hope and pray for a speedy recovery for our employee. We hope and pray her family doesn’t become ill, [and] we hope and pray we don’t!” the owners of Lisa’s Western Cuisine & Spirits wrote on Facebook. “Mostly, we hope and pray that by acting quickly, we will not have encouraged the spread of this dreadful ravish.”

As of Monday, Big Horn County had four active cases of COVID-19 while Washakie County — which has seen three deaths related to the disease from a Worland nursing home — had 16 active cases.

Both of Park County’s two confirmed cases have recovered, as have eight people known to have been infected with the disease in Hot Springs County; a new case in Hot Springs County was reported Monday.

With only two positive tests amid a population of nearly 29,200 people, Park County has had the lowest prevalence of confirmed COVID-19 cases in the state. Since March, more than 600 tests have been run on samples collected from people in Park County. That’s among nearly 1,600 tests run on samples from around the Big Horn Basin as of Monday.

Across the state of Wyoming, there were 170 active confirmed or probable cases of the disease on Monday (21 of them in the Big Horn Basin), with seven people hospitalized (none in the Basin). Dr. Billin said those are some of the most important numbers to watch and “both of these numbers have been going down, which is very reassuring,” he said Sunday.

Most people who become infected with the disease suffer from mild or moderate symptoms and recover at home, but COVID-19 can be more serious or deadly, particularly for older residents and people with certain health conditions.

Billin continued to defend the restrictions that the county and the state have put in place to curb the spread of the novel coronavirus.

“Wyoming has had one of the least restrictive responses to COVID-19 in the nation and one of the lowest death rates per capita,” he wrote on Sunday. “That’s a pretty good return on investment.”